Superparamagnetic iron oxide
Date of this Version
The field of molecular imaging has recently seen rapid advances in the development of novel contrast agents and the implementation of insightful approaches to monitor biological processes non-invasively. In particular, superparamagnetic iron oxide nanoparticles (SPIO) have demonstrated their utility as an important tool for enhancing magnetic resonance contrast, allowing researchers to monitor not only anatomical changes, but physiological and molecular changes as well. Applications have ranged from detecting inflammatory diseases via the accumulation of non-targeted SPIO in infiltrating macrophages to the specific identification of cell surface markers expressed on tumors. In this article, we attempt to illustrate the broad utility of SPIO in molecular imaging, including some of the recent developments, such as the transformation of SPIO into an activatable probe termed the magnetic relaxation switch.
You might also like
Sealmaster NP-19 Pillow Block Ball Bearing, Non-Expansion Type, Normal-Duty, Regreasable, Setscrew Locking Collar, Felt Seals, Cast Iron Housing, 1-3/16" Bore, 1-11/16" Base to Center Height, 4-3/4" Bolt Hole Spacing Width
Cobra Carbide 40933 Solid Carbide Turning Insert, CM02 Grade, Multilayer Coated, TCMT Style, TCMT 21.51, 3/32" Thick, 1/64" Radius (Pack of 10)
BISS (Cobra Carbide)